You can find it in urine, sweat, blood and milk in mammals. There is a huge market for urea for numerous purposes so production is very high. Urea 40% Cream 1 oz. Scientist have learned to synthesize it and it is used for many different purposes. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Urea is made when carbon dioxide is reacted with anhydrous ammonia. These two materials are combined under high pressures and elevated temperatures to form ammonium carbamate, which then decomposes at much lower pressures to yield urea and water . It may also be used to soften nails. All prescription substitutions and/or recommendations using this product shall be made subject to state and federal statutes as applicable. Urea Cream 40%. While glucose, water and salts are reabsorbed into the blood, urea is not. The raw materials are ammonia and carbon dioxide. Urea, also known as carbamide-containing cream, is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis. Apply Urea 40% to affected skin twice per day, or as directed by your physician. Urea 40% cream is a potent keratolytic that is not suitable for use as a regular moisturizer. It increases moisture in the skin by softening/dissolving the horny substance (keratin) holding the top layer of skin cells together. You can use urea cream topically as a skin moisturizer. Rub in until completely absorbed. Claire is a writer and editor with 18 years' experience. The Urea found in cosmetics and personal care products is synthetic and not animal derived. This medication is to be used as directed by a physician and should not be used to treat any condition other than that for which it was prescribed. It was the first organic chemical compound ever synthesized. When applied to the skin, urea causes the skin to retain moisture, which helps to reduce dryness. If you have a urea cycle disorder or a genetic disease, your body cannot safely detoxify ammonia. The lungs get rid of excess carbon dioxide, the skin eliminates excess water and salts, and the kidneys remove excess water, salts and urea. It is formed from ammonia and carbon dioxide and can be produced in either a solid or liquid form. Not for ophthalmic use. Manufacturers like it, though, because it slows the loss of moisture from a product during use, helping to extend shelf-life. Urea forms when dietary proteins make amino acids after digestion. People often get confused by these, but they are, in fact, … Other brands: Aluvea, U40, Utopic, Urevaz, ... +25 more, Eucerin, AmLactin, Temovate, ammonium lactate topical, Aquaphor, dimethicone topical, CeraVe, urea topical, Clobex, Carmol. Urea is also in animal feedstock, certain plastics and glues, explosive components and commercial products. How Supplied. Available for Android and iOS devices. Urea is a crystalline compound, and the nitrogen content is always at least 46 percent when dry. Each person recommending a prescription substitution using this product shall make such recommendations based on each person's professional opinion and knowledge, upon evaluation of the active ingredients, excipients, inactive ingredients and chemical information provided herein. Ammonia is highly toxic and would be deadly if it accumulated in the body. Urea Nail Gel is available in many different forms (cream, lotion, ointment, liquid, gel, foam, shampoo, and others) for use on the skin or the scalp. The German chemist Friedrich Wohler in 1828 attempted to make ammonium cyanate from silver cyanide and ammonium chloride and, in the process, accidentally made urea. How does Urea work? skinpharmacies.ca. Urea is synthesized in the body of many organisms as part of the urea cycle, either from the oxidation of amino acids or from ammonia. It passes out of the body as a solution in water, which you know as urine. Carbohydrates are broken down into sugars through a number of enzymatic processes, which can then be metabolized for energy. Enriched with Urea and Lactate, two naturally occurring compounds that bind in moisture, it instantly hydrates dry facial skin, reducing the feeling of tightness.In addition to reducing roughness by maintaining skin hydration (rough skin is often caused by a lack of moisture), The urea cycle starts with deamination, when the liver breaks down amino acids to make ammonia. You can find it in urine, sweat, blood and milk in mammals. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis palmaris, keratoderma, corns and calluses, as well as damaged, ingrown and devitalized nails. She writes about science and health for a range of digital publications, including Reader's Digest, HealthCentral, Vice and Zocdoc. Urea is an over-the-counter (OTC) product used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e.g., diaper rash, skin burns from radiation therapy). While shopping online for an skin creams with urea is easier and more convenient than shopping in person, it is also harder to know if you are buying a high-quality product. Known hypersensitivity to any of the listed ingredients. The body uses this type of urea in the same way as the urea naturally found in the skin. The majority of the food that we eat can be categorized as either fats, proteins or carbohydrates, all of which can produce energy for the body when it is metabolized or broken down. Urea, sometimes referred to as carbamide, is produced in mammalian systems when proteins are broken down. Urea 40% is a keratolytic emollient which is a gentle, yet potent, tissue softener for nails and/or skin. For further information about unapproved drugs, click here. It may also be useful to treat dry skin in older adults. Urea was the first organic chemical made from inorganic ones. Avoid contact with eyes, lips or mucous membranes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This process happens under intense pressure, at 350 degrees Fahrenheit. Urea is of major historical significance. Urea cream typically ranges from 2% to 40% in potency and is used to help soften thick layers of skin and nails, also it decreases itching. Transient stinging, burning, itching or irritation may occur and normally disappear upon discontinuing the medication. Animal reproduction studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. US $2.00-$2.52 / Piece 600 Pieces (Min ... 1,389 urea cream products are offered for sale by suppliers on Alibaba.com, of which foot skin care accounts for 6%, hand cream & lotion accounts for 2%, and lids, bottle caps, closures accounts for 1%. The kidneys remove urea, as well as glucose, water and salts, by filtering blood at high pressures. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. About one million pounds of urea is manufactured in the United States each year, most of it for fertilizers due to its high nitrogen content, which makes it water soluble. For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eshar. Scientist have learned to synthesize it and it is used for many different purposes. For topical use only. Emollients are substances that soften and moisturize the skin and decrease itching and flaking. Urea is a natural substance made in the body to help with the metabolism and excretion of nitrogen. Each person recommending a prescription substitution using this product shall make such recommendations based on each person's professional opinion and knowledge, upon evaluation of the active ingredients, excipients, inactive ingredients and chemical information provided herein. skinpharmacies.ca. KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN. Royal Society of Chemistry: Excretion and the Liver, University of Bristol School of Chemistry: Urea, The George Washington University: Urea Cycle Disorders. (4) Last updated on May 1, 2020. Urea Cream Compounded . Ammonium cyanate is urea." (85 g): NDC 16477-340-03; Urea 40% Cream 7 oz. Urea consists of carbon, nitrogen and oxygen. The mechanism of action of topically applied urea is not yet known. Urea is part of the natural moisturizing factor (NMF) of skin, which is made up of 40% amino acids, 12% sodium PCA, 9% glycerol, and 8.5% urea (among other things). Description. Urea also acts to remove dead skin, states the University of Pittsburgh Medical Center. Urea 40% is a keratolytic emollient which is a gentle, yet potent, tissue softener for nails and/or skin. Enriched with Urea (10%), this super cream eliminates scales [...] and tugging sensations. Temperature 15°C - 30°C ( 59°F - 86°F ) no representation is from... 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