Indeed, there’s lots to talk about. Avocado flesh’s high fat content can lead to gastrointestinal upset and pancreatitis in dogs if they eat too much, and because it’s calorie-dense, it can also lead to weight gain. The first three sentences in the study’s conclusion can sound quite scary…, “To conclude our study suggests that the extracts of both avocado fruit and leaves can potentially induce significant genomic instability and some genetic damage in human lymphocytes in vitro. When an oil is heated past its smoke point , it generates toxic fumes and free radicals which are extremely harmful to your body. It appears the leaves are potentially more poisonous to DNA. 500 mg/kg dose = 20% mortality after 24 hours. It acts as a natural fungicide. The growth of new skin is facilitated by the use of avocado oil as it is rich in potassium and lecithin in abundance when compared to other oils. The 10 Healthiest and Least Healthy Oils to Cook With | Time This causes lesions which may result in cell death or mutations. While all 3 of the diets “significantly decreased” LDL and total cholesterol versus baseline, look which one did best: Being chock full of fat, one would assume that frequent consumption would lead to obesity. But even ignoring that, the creamy consistency is something that just about anyone finds satisfying. This isn’t exactly breaking news. One of the serious side effects of avocados is that it can damage liver health. The fact that it’s not being done is no surprise. Published in 2013 by researchers in Guadalajara, Mexico is another study titled (7): Acute Toxicity and Genotoxic Activity of Avocado Seed Extract (Persea americana Mill., c.v. Hass). There have been at least eight human studies conducted and while most were quite small, their findings seem to suggest a similar conclusion; this food has a beneficial effect on blood lipids. ConsumerLab's answer explains. You should consult with a physician before starting any diet, exercise or supplementation program, or if you have or suspect you might have a disease. So right now, one can ask the question if it is toxic, but no one can claim it is toxic to humans after consumption. Reviewed and edited by Tod Cooperman, M.D. Sometimes after I eat avocado, I feel nauseaus, kind of vomitting feeling. Because as of right now, the effects in vivo (in the human body) have not been studied. As you see, the number seen in all 3 concentrations is much higher than the control group (when no avocado is added). Afterward, they checked to see if any DNA damage occurred. Extra virgin olive oil has a smoke point of 375 – 400 degrees while avocado oil has a smoke point of 500 degrees. In theory, this “good” fat content should not have changed things though, since the other moderate fat diet had also used the same ratio of monounsaturated fats, albeit from different sources. Or should consumption be lowered to half of a whole avocado on any day? There’s no proof of that. Side Effects You’d Never Expect, Review: Mustard Bath Recipes Don’t Detox, But They Do This, 25 Myrrh Essential Oil Uses & Gum Benefits Being Studied, How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease. Now, a report 1, 2, 3 in the journal Food Control warns that the purity and quality of avocado oil sold in the U.S. is questionable at best, and that standards to protect consumers and genuine producers are urgently needed. But as with any food, just because we don’t notice side effects, that doesn’t always guarantee it’s safe to eat. ConsumerLab.com's answer explains. They are waiting until this topic is further researched. When they do cause permanent alterations, then they are both a genotoxin and a mutagen. As mentioned, Petri dish toxicity is different than what might happen after the substance has been digested. 1,000 peripheral reticulocytes (immature red blood cells) were analyzed per mouse. Persin is a fungicidal toxin present in the avocado. So weird. Everyone, from mainstream media to niche nutritional sites, all love to praise the many benefits of eating avocado. This site is for informational purposes only and is not intended as a substitute for advice from your physician. All mutagens are genotoxic, but not all genotoxins are mutagens. Research has suggested a number of reasons why they may be good for you to eat on a regular basis, even when you’re on a diet. Avocado oil has a similar monounsaturated fat profile to olive oil. That all begun to change in the late 90’s. When purified, the toxic principle in avocado, persin, causes mastitis in lactating mice at 60–100 mg/kg, and dosages >100 mg/kg result in myocardial necrosis. Avocado Cuticle Oil with Lavender - Nail Treatment; Non-Toxic, Vegan, and Cruelty-Free (#19628)-The Avocado Beauty Oil works great on cuticles or all Free Shipping on … Many clinical studies and pieces of research touting the advantages of avocados are funded, at least in part, by marketers of this produce. The study is interesting since it involves ingestion of an avocado, unfortunately it’s using animals and did not involve the flesh of the fruit which is what people consume. Is avocado oil safe to use? With those caveats said, there is at least some in vitro evidence which suggests that avocados might be bad for you, if the same reactions seen in the laboratory also occur inside the human body after digestion. Not only did DNA damage occur, but it seemed to be quite prevalent. As seen in the study, it was also the leaf extract which demonstrated in vitro toxic effects which were significantly worse. Carefully-processed avocado oil retains many of those nutrients. The one known poison in avocados is something called “persin.” Persin is a natural antifungal compound that can be produced within the avocado plant. Before you abstain from that great avocado on your salad, it’s important to keep in mind that: In short, what happens in a Petri dish may or may not happen in the human body. The genotoxic effect on germ cells of adults could lead to infertility, recurrent abortions, early fetal loss, or inherited defects in their offspring.“. Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will posts that exceed 2,500 characters. Persin is an oil-soluble compound structurally similar to a fatty acid, and it leaches into the body of the fruit from the seeds. There are at least 59 research papers listed in the FDA poisonous plant database about this poison affecting ostriches, goats, mice, rats and other species (6). Far from it, in fact. As humans it has been theorized that every day, our body experiences anywhere from 10k to 1M molecular lesions (4). Helps Psoriasis and Other Skin Problems. Toxic Principles: Toxic to horses, cattle, goats, and birds. Me too! To avoid confusion though, this study did not claim it is something for you to eat to lose weight. Seems like sensitivity or reaction. They contain a small amount of a natural toxin called persin [ ( R, 12 Z ,15 Z )-2-Hydroxy-4-oxohenicosa-12,15-dienyl acetate]. Avocado is highly toxic to horses, goats, birds, and cattle, and with dogs, depending on the amount they consume, can end up with an upset stomach. We don’t suffer the side effects that the aforementioned animals do when they eat avocado. We already know that it contains a poison which is toxic to many animals, but safe in humans (more on that below). This is because of a poison they contain called persin. The same is true for peanut oil, grapeseed oil, soybean oil, sunflower oil, and safflower oil. Mentally I feel spaced out and I get fatigued. The bad news. Answer: There is no reason to believe that avocado oil is unsafe. While the current opinion is now somewhat divided as to their toxicity in dogs and cats, the consensus among scientists seems to be in agreement that avocados are poisonous to birds, rabbits, horses, pigs, cows, and some other large animals. That quote was expressed in a video a few years back by Dr. Michael Greger, in reference to the 2010 study. The easy answer is: Yes. “Most people who buy avocado oil are interested in the health benefits, as well as the mild, fresh flavour, and are willing to pay more for the product. The Many Health Benefits of Avocados. Different from that topic, there is also research which used in vitro testing and the results suggest it might be genotoxic to human blood cells (we stress the word might, don’t jump to conclusions yet). For you or your wife during pregnancy, that quote can sound particularly frightening. Even people who hate veggies think they’re good. It is a fungicidal toxin, which is harmful for livestock. Chosen Foods claims that their refinement process retains 80 percent of the beta-sitosterol found in virgin avocado oil, as well as 60 percent of the vitamin E!. Kevala Avocado Oil. The Guatemalan variety, a common one found in stores, appears to be the most problematic. There are certain types of avocado oil which may cause damage to your liver. Though not all are repairable and some slip through the cracks. This morning I have painfull acid reflux. As a side benefit, you can also use avocado oil … Best Bioavailability: Ubiquinol vs. Ubiquinone, Liquid CoQ10, Top 10 Superfoods of 2020 (Science-Based, Not Hype), Nature’s Way Turmerich Joint & Heart Supplements Reviewed, Pili Nuts Nutrition and 9 Science-Backed Benefits. This site is intended for informational purposes only and not to provide medical advice. Even if persin is not poisonous to humans, some wonder if it might play a role in the genotoxicity seen in vitro. Goats develop severe mastitis when ingesting 20 g of leaves/kg, whereas 30 g of leaves/kg results in cardiac injury. Yes they’re high calorie, but also high fiber; providing you with 40% of the daily value for that same aforementioned serving size. 24/7 ANIMAL … If the same effect occurs on somatic cells in vivo, it could result in loss of function, apoptosis, or neoplastic trans- formation of those cells. I ate avo 2 days ago I noticed when I finished that it has a bitter taste, yesterday my lips swell, body itchy, sore throat. 23% increased satisfaction after eating their lunch versus the control group, 28% decreased desire to eat following lunch. The cetane numbers of avocado oil methyl esters and olive oil methyl esters are relatively high, determined as 59.2 and 62.5, respectively, due to their elevated content of methyl oleate. If you are doing high heat cooking, use avocado oil instead. For some reason I feel off when I eat them. Is magnesium citrate safe? The fact that most olive oils on the market are fraudulently diluted with less expensive (and more harmful) oils has been known for years. I’m starting to believe that the poison persin found in many parts of the Avocado might be affecting us after all. The first study we will address was published in 2010 (5). No ones claiming they’re a low calorie food. Chemical or physical agents which have the ability to damage DNA. This is actually one of the more mild photos, as some others showed higher numbers of mutations which included: Even more worrying was that they tested 3 different dosages; 100 mg/kg, 200 mg/kg, and 300 mg/kg. Therefore, it’s hard to conclude much from this study, either. The most toxic portion of an avocado is the leaf. Those 3 things are just a few of the numerous avocado health benefits which have been suggested to date. Aside from the danger of death, pregnancy complications and risks while breastfeeding their babies are concerns with some livestock. Animals can suffer from diarrhea or vomiting on consuming the leaves or bark. The bad news is that the oil of avocado will have very little antioxidants relative to the fresh fruit. Avocado poisoning in dogs occurs when dogs ingest the pit of an avocado. Persin is an oil-soluble compound found in the leaves and bark of the avocado plant as well as the pits. I feel dizzy and a bit spaced out mentally after eating one. Avocado leaves, fruit, seeds and bark may contain a toxic principle known as persin. There seems to be no end in sight of booming growth for this crop. Superfoodly is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com. Why exactly it increased satiability is unknown. It was conducted at a cancer hospital and research center in India. Before You Reach For That Oil … Karen Allen expressed concern over the increasing popularity in avocado-based products — Does Sambucol Black Elderberry Really Work For Colds & Flu? Both canola and vegetable oil are so highly processed and refined, that they are toxic for your health! Avocado oil is naturally low acidic, helping to increase smoke point. / The results were as follows…, “There is no statistically significant difference between the group administered with the extract of P. americana seed and control group; however, there is a significant difference between both these groups in regard to the positive control.”. Other varieties may produce oils of slightly different flavor profile; 'Fuerte' has been described as having more mushroom and less avocado flavor. Published in a 2013 edition of Nutrition Journal, this randomized crossover study involved 26 overweight people (3). Therefore, it is considered that the P. americana seed extract showed no genotoxic activity with the micronucleus test. They were broken up into 3 groups, each receiving a different lunch; avocado-free, avocado inclusive, or avocado added. Though as mentioned, they said this was not statistically significant. The positive control – colchicine – is medication used to treat gout. If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product. It is those unrepaired genetic alternations which might lead to problems. Basically, the researchers took avocado and diluted it in a solution, which was then dripped on healthy human white blood cells which were alive in a Petri dish. These were administered to the mice using an orgastric tube (a dropper). Blood samples weren’t collected until 36 hours later. Source: USDA, Economic Research Service, 2016. While nothing more than a theory, it is interesting to note that the leaves, bark, skin, and pit of the fruit have the higher concentrations of persin… not the fruit. Avocado Is Toxic To Dogs Clinical signs are agitation, aggression, vomiting, diarrhea, drooling, tremors, & respiratory or cardiovascular depression. While it is true that effects of colchicine are off the charts relative to the alcohol-water and the avocado pit extract solutions, notice how the number for the pit is still higher versus the alcohol-water solution (16.4 vs. 10.6). I heard that it might cause damage to the esophagus. But is there a dark side to this delicious fruit? www.consumerlab.com/answers/is-avocado-oil-safe-to-use/avocado-oil-safety/. The same pattern is seen in the leaf extract, which were also tested using the 3 different dosages. Which Curcumin Supplement Has The Best Absorption? Whether they “passed” the test was simply whether they were alive or dead after 24 hours. Before you ditch your bottle of EVOO and get that gallon of avocado oil at Costco, you need to hear about the genotoxic and mutagenic side effects which have been observed in the lab. For your privacy, only your first name (from your account) followed by a random number will appear with your comment. Definitely seems like a marketing ploy to increase sales. Find out if canola oil is bad for you or good for you, and whether it helps heart health. Results indicated that avocados are highly toxic to budgerigars and less toxic to canaries. Beyond Meat Vegan Sausage Review: Gluten Free, Best Brand? Is it okay for a human adult to eat a whole avocado for lunch or with salad? I’m starting to wonder about all this health craze for Avocados. Can supplements improve symptoms of dry eye? The title of the study is: In vitro evaluation of genotoxicity of avocado (Persea americana) fruit and leaf extracts in human peripheral lymphocytes. Those who have a vested interest in selling them and highlighting their many great traits. Thanks to marketing and more widespread adoption of other cultural cuisines, the per capita consumption of avocado is nearly 400% higher than it was 20 years ago (1). Clinical evidence and how it compares to other oils. Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.© 2020 Superfoodly, 1. Even the authentic Mexican restaurants in many parts of the country wouldn’t incorporate avocado in their dishes, due to limited supply and high cost. While similar in definition, the term genotoxin should not be confused with mutagen. ConsumerLab.com name and flask logo are both registered trademarks of ConsumerLab.com, LLC. Guacamole contains a good amount of water, quite a bit of phosphorus, a hint of calcium and sugar, a lot of acidic content, carbohydrates and fat. Is Canola Oil And Veggie Oil Bad For Me? What about the avocado oil used in things like Primal Kitchen Mayo? Both unrefined and refined avocado oil can safely be used for … Aside from the part tested, there were some other major differences: As far as acute toxicity (lethal poisoning) there were not deaths using the lower dosages, but it did produce death at 500 mg/kg and above: For the genotoxicity test, the blood samples (which remember, weren’t harvested until 36 hours had passed), were viewed under a fluorescence microscope. This one isn’t very relevant, since they were only looking at the potential toxicity of the seed extract. While the current opinion is now somewhat divided as to their toxicity in dogs and cats, the consensus among scientists seems to be in agreement that avocados are poisonous to birds, rabbits, horses, pigs, cows, and some other large animals. One of the most recent – and largest – was carried out by Pennsylvania State University and published in 2014 (2). Instead, the vast majority of the research suggests we actually experience benefits of health instead, such as those mentioned at the start. We heard from one woman who was avoiding them while pregnant. Avocado oil is commonly used as a carrier oil for essential oils. The higher the amount of avocado used, the higher the number chromosomal mutations. Foods and supplements discussed on this site are not intended to diagnose, treat, cure, or prevent any disease. Avocado Seeds Are Toxic to Livestock Persin is present in the bark and leaves of avocado plants and soluble in oil. As explained in the Safety section of our other posting about avocado oil, some people may have an allergic reaction to avocado, and the oil may interact with the blood-thinner warfarin, but these are not common issues. Avocado is not toxic to cats, and according to ASCPA, avocado is safe for cats. The reason why they were testing it was because some cultures use seed derivatives as an herbal remedy for various diseases. Ive gone carnivore and feel better than i have in 52 years…..was hoping to ad avocados back, but never mind….not that big of a deal. The oil is extracted from ripened fruit in which the meat pulp has been separated from the skin and the pit.” Morgan Swofford for LittleThings Is Avocado Toxic For Dogs? © 2020 ConsumerLab.com, LLC. The additional 5 grams of fiber may have played a part. As an Amazon Associate we earn from qualifying purchases. They wanted to compare 3 different diets which were believed to have cholesterol lowering effects: Avocados are an excellent source of monounsaturated fats. Likewise for the one about LDL cholesterol in overweight adults, which looked at the effect that fruit had while dieting. That same serving size provides the following percentages for your daily value of: This food is also a natural source of the antioxidants lutein and zeaxanthin, which research has associated with eye health. I honestly am trying to avoid them altogether. Until the jury is in, I think it’s reasonable given this new data, for people to consider reducing their intake. However in humans, persin is considered to be completely safe, including for pregnant women and those who are breastfeeding. These 50 Foods Are High In Lectins: Avoidance or Not? Helps in Skin Growth. Other varieties of … The relatively low concentrations of persin in the ripe pulp of the avocado fruit is generally considered harmless to humans. Despite being around for several years now, it seems almost no one discusses it. Vitamins, minerals, and phytonutrients, Coconut Nectar Benefits For Glycemic Index Are Deceptive, 12 Manuka Oil Benefits Scientifically Analyzed, Is Hot Sauce Good For You? Cancer is caused by mutations to the DNA. The acute toxicity test used the following dosages; 125, 250, 500, 1,000, and 2,000 mg/kg. You will see very detailed articles reviewing the benefits of avocado and the authors sometimes even discuss  possible (yet unproven) side effects, but they seem to be totally oblivious to this genotoxicity research. If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study. This much is true: Most parts of the avocado plant contain an oil-soluble compound called persin, which is thought to be the primary toxin. The levels of persin vary between the different types of avocados other external factors. That’s why the very last sentence of the conclusion is; “Thus, it is essential to carry out in vivo studies for genotoxicity before making a final remark on the genotoxicity of the plant extract.”. Toxicity to Animals of Avocado Oil Avocado is documented to be harmful to some animals; such as cats, dogs, cattle, goats, rabbits, rats, guinea pigs, birds, fish, and horses can be severely harmed or even killed when they consume them. Thus, consumption of these may cause damage to the liver. He is a leader in nutritional research and author of the New York Times bestseller How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease. The fine print is that this group was also consuming an extra 112 calories, which likely has something to do with it. These are bad for you, but fortunately it is believed our body is able to repair most of them. Okay for a human adult to eat following lunch some slip through cracks! Discussed on this site is for informational purposes only and is not poisonous to.... Is something that just about anyone finds satisfying I heard that it might a... 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